Multiple bowel polyps

Gene: SMAD4

Green List (high evidence)

SMAD4 (SMAD family member 4)
EnsemblGeneIds (GRCh38): ENSG00000141646
EnsemblGeneIds (GRCh37): ENSG00000141646
OMIM: 600993, Gene2Phenotype
SMAD4 is in 27 panels

1 review

Ian Frayling (Cardiff University)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

History Filter Activity

1 Mar 2016, Gel status: 4

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for SMAD4 was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

29 Jan 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

28 Aug 2015, Gel status: 3

Added New Source

Ellen McDonagh (Genomics England Curator)

SMAD4 was added to Multiple bowel polypspanel. Source: Eligibility statement prior genetic testing

28 Aug 2015, Gel status: 3

Added New Source

Ellen McDonagh (Genomics England Curator)

SMAD4 was added to Multiple bowel polypspanel. Source: UKGTN

28 Aug 2015, Gel status: 2

Added New Source

Ellen McDonagh (Genomics England Curator)

SMAD4 was added to Multiple bowel polypspanel. Source: Emory Genetics Laboratory

28 Aug 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

SMAD4 was added to Multiple bowel polypspanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,UKGTN,Eligibility statement prior genetic testing