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Prostate cancer pertinent cancer susceptibility

Gene: MLH1

Green List (high evidence)

MLH1 (mutL homolog 1)
EnsemblGeneIds (GRCh38): ENSG00000076242
EnsemblGeneIds (GRCh37): ENSG00000076242
OMIM: 120436, Gene2Phenotype
MLH1 is in 35 panels

1 review

Ellen McDonagh (Genomics England Curator)

This gene was added after request from Clare Turnbull (Cancer Clinical Team, Genomics England), and confirmed by Lara Hawkes (Cancer Clinical Team, Genomics England) that this addition is correct.
Created: 20 Aug 2018, 1:26 p.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert list
  • Expert Review Green
OMIM
120436
Clinvar variants
Variants in MLH1
Penetrance
None
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 4

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: This gene was added after requ

27 Jul 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

MLH1 was added to Prostate cancer pertinent cancer susceptibility panel. Sources: Expert Review Green,Expert list

27 Jul 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

MLH1 was created by Ellen McDonagh