Inherited non-medullary thyroid cancer

Gene: MINPP1

Red List (low evidence)

MINPP1 (multiple inositol-polyphosphate phosphatase 1)
EnsemblGeneIds (GRCh38): ENSG00000107789
EnsemblGeneIds (GRCh37): ENSG00000107789
OMIM: 605391, Gene2Phenotype
MINPP1 is in 2 panels

3 reviews

Sarah Leigh (Genomics England Curator)

Publications

Emma Woodward (Manchester Centre for Genomic Medicine)

Red List (low evidence)

insufficient evidence linking germline mutation with NMTC predisposition
Created: 13 Jun 2017, 2:18 p.m.
insufficient evidence linking germline mutation with NMTC predisposition
Created: 13 Jun 2017, 2:18 p.m.

Fiona Lalloo (Manchester Centre for Genomic Medicine)

Red List (low evidence)

A single publication with one case of follicular thyroid ca and one adenoma. No other evidence available. No clinical utility
Created: 9 Jun 2017, 9:25 a.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Thyroid carcinoma, follicular 188470
OMIM
605391
Clinvar variants
Variants in MINPP1
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

7 Aug 2017, Gel status: 1

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

All genes have been reviewed and the reviews evaluated. 07.08.2017

18 May 2017, Gel status: 0

Created

Sarah Leigh (Genomics England Curator)

MINPP1 was created by sleigh

18 May 2017, Gel status: 1

Added New Source

Sarah Leigh (Genomics England Curator)

MINPP1 was added to Inherited non-medullary thyroid cancerpanel. Sources: Radboud University Medical Center, Nijmegen