Inherited non-medullary thyroid cancerGene: VTRNA2-1
Over expression of VTRNA2-1 in thyroid cancer cell lines increased the number of cells in S phase and inhibited cell proliferation, formation of spheroids in suspension cultures, and cell migration in adherent cultures, this was associated with increased CDC6 (602627) protein expression and activity (PMID 21998631).
Created: 7 Aug 2017, 1:03 p.m.
no evidence of clinical utility
Created: 13 Jun 2017, 3:50 p.m.
Tag locus-type-rna-vault tag was added to gene: VTRNA2-1.
All genes have been reviewed and the reviews evaluated. 07.08.2017
VTRNA2-1 was created by sleigh
VTRNA2-1 was added to Inherited non-medullary thyroid cancerpanel. Sources: Literature