Infantile enterocolitis & monogenic inflammatory bowel diseaseGene: ICOS
Associated with phenotype in OMIM, not in G2P / DD. Present on UKGTN Very Early Onset Inflammatory Bowel Disease 40 Gene Panel and Emory Genetics Laboratory Early Onset Inflammatory Bowel Disease: Sequencing Panel. Four homozygous variants reported
Created: 5 Sep 2016, 6:51 a.m.
14th Oct 2016: panel revised according to expert review, additional curation for evidence level and internal clinical review, and promoted to version 1.
ICOS was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen,UKGTN
Phenotypes for gene ICOS were set to Immunodeficiency, common variable, 1 607594
ICOS was created by ellenmcdonagh
ICOS was added to Infantile enterocolitis & monogenic inflammatory bowel diseasepanel. Sources: Expert list