Complex Parkinsonism (includes pallido-pyramidal syndromes)Gene: GCH1
Comment on list classification: Is on the Complex Parkinson's Disease/Dystonia NGS Panel in the UCLH National Hospital for Neurology and Neurosurgery & Institute of Neurology (NHNN) Neurogenetics genetic testing manual, and is within the section regarding genetic testing for Parkinson's Disease and Parkinsonism for dopa responsive dystonia: "This may sometimes present as a young onset parkinsonian syndrome with or without dystonia. Patients are very responsive to L-dopa and the disease gene that should be tested in most instances is the GCH1 gene."
Created: 10 Jun 2016, 10:51 a.m.
This gene has been classified as Green List (High Evidence).
GCH1 was created by ellenmcdonagh
GCH1 was added to Complex Parkinsonism (includes pallido-pyramidal syndromes)panel. Sources: Expert list