Complex Parkinsonism (includes pallido-pyramidal syndromes)

Gene: PANK2

Green List (high evidence)

PANK2 (pantothenate kinase 2)
EnsemblGeneIds (GRCh38): ENSG00000125779
EnsemblGeneIds (GRCh37): ENSG00000125779
OMIM: 606157, Gene2Phenotype
PANK2 is in 13 panels

1 review

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Is on the Complex Parkinson's Disease/Dystonia NGS Panel in the UCLH National Hospital for Neurology and Neurosurgery & Institute of Neurology (NHNN) Neurogenetics genetic testing manual. Also in the GeneReviews Neurodegeneration with Brain Iron Accumulation Disorders Overview, list of the genetic basis of ten types of NBIA (http://www.ncbi.nlm.nih.gov/books/NBK121988/).
Created: 10 Jun 2016, 11:14 a.m.

History Filter Activity

10 Jun 2016, Gel status: 4

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for PANK2 were set to Early Onset Complex Disease; Dystonia; pantothenate kinase-associated neurodegeneration

10 Jun 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

24 Jul 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

PANK2 was added to Complex Parkinsonism (includes pallido-pyramidal syndromes)panel. Sources: Expert