Left Ventricular Noncompaction Cardiomyopathy

Gene: TNNI3

Red List (low evidence)

TNNI3 (troponin I3, cardiac type)
EnsemblGeneIds (GRCh38): ENSG00000129991
EnsemblGeneIds (GRCh37): ENSG00000129991
OMIM: 191044, Gene2Phenotype
TNNI3 is in 7 panels

1 review

Oxford Medical Genetics Laboratory (OUH NHS Foundation Trust)

Red List (low evidence)

Good functional candidate. However, to date no pathogenic TNNI3 variants have been detected (i.e. as described in literature or in our lab) in individuals with LVNC.
Created: 6 Jan 2016, 5:12 p.m.

History Filter Activity

11 Feb 2016, Gel status: 1

Gene classified by Genomics England curator

Caroline Wright (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

12 Aug 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

TNNI3 was added to Left ventricular non-compaction cardiomyopathypanel. Sources: Eligibility statement prior genetic testing