Familial cicatricial alopecia

Gene: GJA1

No list

GJA1 (gap junction protein alpha 1)
EnsemblGeneIds (GRCh38): ENSG00000152661
EnsemblGeneIds (GRCh37): ENSG00000152661
OMIM: 121014, Gene2Phenotype
GJA1 is in 24 panels

1 review

Rebecca Foulger (Genomics England curator)

Comment on list classification: Changed rating from Red to Grey: congenital alopecia phenotype is too broad for this cicatricial (scarring) alopecia panel.
Created: 11 Jul 2017, 8:37 a.m.

History Filter Activity

26 Feb 2021, Gel status: 0

Added Tag

Arina Puzriakova (Genomics England Curator)

Tag curated_removed tag was added to gene: GJA1.

20 Jul 2017, Gel status: 0

panel promoted to version 1

Rebecca Foulger (Genomics England curator)

20 July 2017: Reviews from Prof. John McGrath were assessed, and panel was revised largely to reflect his expert review. Demoted FOXN1 and GJA1 to grey because the congenital alopecia phenotype is too broad for this cicatricial (scarring) alopecia panel. For most of the red genes, there is only very minor (often indirect) evidence to support a link to cicatricial alopecia, but they remain on the panel, for now, for completeness.

11 Jul 2017, Gel status: 0

Gene classified by Genomics England curator

Rebecca Foulger (Genomics England curator)

This gene has been removed from the panel.

22 Nov 2016, Gel status: 0

Created

Rebecca Foulger (Genomics England curator)

GJA1 was created by rfoulger

22 Nov 2016, Gel status: 1

Added New Source

Rebecca Foulger (Genomics England curator)

GJA1 was added to Familial cicatricial alopeciapanel. Sources: Radboud University Medical Center, Nijmegen