Familial prostate cancer

Gene: CHEK2

Red List (low evidence)

CHEK2 (checkpoint kinase 2)
EnsemblGeneIds (GRCh38): ENSG00000183765
EnsemblGeneIds (GRCh37): ENSG00000183765
OMIM: 604373, Gene2Phenotype
CHEK2 is in 8 panels

1 review

Ellen McDonagh (Genomics England Curator)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
{Prostate cancer, familial, susceptibility to}

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Literature
Phenotypes
  • {Prostate cancer, familial, susceptibility to}
OMIM
604373
Clinvar variants
Variants in CHEK2
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

7 Mar 2017, Gel status: 0

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

07/03/2017 - revised and ready to promote to version 1.

26 Jan 2017, Gel status: 0

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for CHEK2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

26 Jan 2017, Gel status: 0

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for CHEK2 were set to {Prostate cancer, familial, susceptibility to}

26 Jan 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

CHEK2 was created by ellenmcdonagh

26 Jan 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

CHEK2 was added to Familial prostate cancerpanel. Sources: Literature