Periodic fever syndromes

Gene: IL1RN

Green List (high evidence)

IL1RN (interleukin 1 receptor antagonist)
EnsemblGeneIds (GRCh38): ENSG00000136689
EnsemblGeneIds (GRCh37): ENSG00000136689
OMIM: 147679, Gene2Phenotype
IL1RN is in 8 panels

1 review

Alice Gardham (Genomics England)

Comment on list classification: The Royal Free Periodic Fever Service class IL-1 receptor antagonist deficiency as an inherited fever syndrome
Created: 2 Feb 2017, 10:44 a.m.

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
Phenotypes
  • Interleukin 1 receptor antagonist deficiency, 612852
  • OMPP
  • DIRA syndrome
  • recurrent fever
OMIM
147679
Clinvar variants
Variants in IL1RN
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

22 Feb 2017, Gel status: 4

panel promoted to version 1

Rebecca Foulger (Genomics England curator)

22nd February 2017: Promoted to V1. Panel was reviewed by Tracy Briggs and Alice Gardham. Panel was revised according to expert review and additional curation.

2 Feb 2017, Gel status: 4

Set publications

Alice Gardham (Genomics England)

Publications for IL1RN were set to 19494218

2 Feb 2017, Gel status: 4

Gene classified by Genomics England curator

Alice Gardham (Genomics England)

This gene has been classified as Green List (High Evidence).

1 Feb 2017, Gel status: 1

Gene classified by Genomics England curator

Alice Gardham (Genomics England)

This gene has been classified as Red List (Low Evidence).

17 Jan 2017, Gel status: 0

Created

Rebecca Foulger (Genomics England curator)

IL1RN was created by rfoulger

17 Jan 2017, Gel status: 0

Added New Source

Rebecca Foulger (Genomics England curator)

IL1RN was added to Periodic fever syndromespanel. Sources: Other