FUS

FUS RNA binding protein
OMIM: 137070, Gene2Phenotype

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Red FUS in Early onset dementia (encompassing fronto-temporal dementia and prion disease)

Level 3: Neurodegenerative disorders
Level 2: Neurology and neurodevelopmental disorders
Version 1.62

review Not set
Sources
  • Expert Review Red
  • UKGTN
Phenotypes
  • Dementia

Green FUS in Neurodegenerative disorders - adult onset


Version 2.57
Latest signed off version: v2.56 (16 Dec 2021)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Wessex and West Midlands GLH
  • Yorkshire and North East GLH
  • NHS GMS
  • London North GLH
  • Expert Review Green
Phenotypes
  • Dementia
  • Amyotrophic lateral sclerosis 6, autosomal recessive, with or without frontotemporal
  • Amyotrophic Lateral Sclerosis, Dominant

Green FUS in Amyotrophic lateral sclerosis/motor neuron disease

Level 3: Neurodegenerative disorders
Level 2: Neurology and neurodevelopmental disorders
Version 1.34

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert
  • Illumina TruGenome Clinical Sequencing Services
  • UKGTN
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Amyotrophic lateral sclerosis 6, autosomal recessive, with or without frontotemporal
  • Amyotrophic Lateral Sclerosis, Dominant