SLC6A4

solute carrier family 6 member 4
OMIM: 182138, Gene2Phenotype

5 panels

Panel Reviews Mode of inheritance Details
5 panels

Red SLC6A4 in Kleine-Levin syndrome

Level 3: Sleep disorders
Level 2: Neurology and neurodevelopmental disorders
Version 1.7

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Red
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • SLC6A4-Related Behavior Disorders
  • {Anxiety-related personality traits} 607834
  • {Obsessive-compulsive disorder} 164230

Red SLC6A4 in Sudden death in young people

Level 3: Cardiac arrhythmia
Level 2: Cardiovascular disorders
Version 1.15

review Unknown
Sources
  • Literature
Phenotypes
  • Sudden infant death syndrome

Red SLC6A4 in Autism


Version 0.27

review Not set
Sources
  • Expert Review Red
  • SFARI

Red SLC6A4 in Paroxysmal central nervous system disorders


Version 1.15
Latest signed off version: v1.14 (16 Dec 2021)

review MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Red
  • NHS GMS
  • London North GLH
  • Wessex and West Midlands GLH
Phenotypes
  • SLC6A4-Related Behavior Disorders
  • {Anxiety-related personality traits} 607834
  • {Obsessive-compulsive disorder}

Red SLC6A4 in Intellectual disability

Level 3: Neurodevelopmental disorders
Level 2: Neurology and neurodevelopmental disorders
Version 3.1002
Latest signed off version: v3.1001 (16 Dec 2021)

Component of the following Super Panels:

  • Hypotonic infant
  • Paediatric disorders
  • White matter disorders - childhood onset
  • review Not set
    Sources
    • Victorian Clinical Genetics Services